Polyphenols, mainly hydrolyzable tannins (212.29 ± 0.005 mg gallic acid equivalent/g of dried DVR), are the main marker class of constituents. DVR samples are cylindrical and microscopically characterized by: a periderm, with six layers of flattened phellem cells, with slightly thickened walls and few layers of phelloderm cortical parenchyma with brachysclereids with a short, roughly isodiametric form (13.82–442.14 μm 2 × 10 3), surrounded by a ring of prismatic calcium oxalate crystals uniseriate medullary rays and prominent vessels of the xylem with single or double shape numerous single and clustered starch grains, within the cortical parenchyma, medullar parenchyma, and ray cells. This includes setting botanical (qualitative and quantitative) and chemical identification parameters, purity tests (loss on drying and total ash), quantifying the major classes of constituents identified, and particle size characterization of the powdered drug. The present work aims at establishing monographic quality criteria to allow the sustainable and safe development of pharmaceutical preparations with this herbal drug.
(De Winter) ( Ebenaceae) is a shrub whose root (DVR) is used as a toothbrush and to treat oral infections in Mozambique.
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